Molecular Cloning of a Novel Scavenger Receptor for ...

2000-12-29 · From a cDNA library of phorbol 12-myristate 13-acetate-stimulated THP-1 cells, we isolated a cDNA encoding a novel protein designated SR-PSOX (scavenger receptor that bindsphosphatidylserine and oxidized lipoprotein), which acts as a receptor for OxLDL. SR-PSOX was a type I membrane protein consisting of 254 amino acids, expression of which was ...Advanced Glycation End Products Induce Vascular Smooth ...2020-8-7 · Steinbrecher U. P., Lougheed M., Kwan W. C., Dirks M. Recognition of oxidized low density lipoprotein by the scavenger receptor of macrophages results from derivatization of apolipoprotein B by products of fatty acid peroxidation. The Journal of Biological Chemistry. 1989; 264 (26):15216–15223. [Google Scholar]

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Function of different proportions of apolipoprotein A-I ...

Abstract. To explore the anti-atherosclerotic effects of recombinant high-density lipoproteins (rHDL) of apolipoprotein AI wild-type (apoA-Iwt), apolipoprotein AI Milano (apoA-IM), apolipoprotein AI (N74C) (apoA-I (N74C) )and apolipoprotein AV (apoA-V). We constructed rHDL liposomes (rHDLs), which included apoA-Iwt, apoA-IM, and apoA-I (N74C), followed by the …Analysis of Macrophage Scavenger Receptor (SR-A ...1999-3-1 · The class A scavenger receptors (SR-As) 1 are trimeric, integral membrane glycoproteins that have been implicated in various macrophage functions, including endocytosis, 1 2 adhesion, 3 phagocytosis, 4 and intracellular signaling. 5 There are 3 forms of the receptor derived by alternative splicing of a single gene. 6 7 8 The 3 isoforms each contain 6 predicted …

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hand 200 tph stone crusher

Stabile Leistung 150 tph Stone Rock Pebble Crusher THP 300 200 Hydraulik kegel brecher Preis. 1.256,00 $8.456,00 $ / Satz. 1 Satz (Mindestbestellung) Zhengzhou General Mining Machinery Co., Ltd. CN 13 YRS.Electronegative LDL Promotes Inflammation and …2020-3-1 · Reverse transcription was performed with 0.5 µg of RNA using EasyScript First-Stand cDNA Synthesis SuperMix (Transgen Biotech, Beijing, China). Quantitative RNA analysis was conducted using RT-PCR in a CFX96 system (BioRad, Hercules, CA, USA).

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(PDF) Erratum: Human (THP1) Macrophages Oxidize LDL …

THP-1 macrophages m, or cell-free controls 0, were incubated in the presence of Hams F10 modification medium, formulated without cystine, containing LDL (100 pg/ml) for 18 h at 37°C. ... :1 Effect of Ac-hE-18A-NH_2,a novel dual-domain apolipoprotein mimetic …

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Autophagy is associated with cell fate in the process of ...

Hypericin-mediated sonodynamic therapy induces autophagy and decreases lipids in THP-1 macrophage by promoting ROS-dependent nuclear translocation of TFEB. 2016 / Xuesong Li, Xin Zhang, Longbin Zheng, Jiayuan Kou, Zhaoyu Zhong, et al. Macrophage Autophagy in Atherosclerosis.Platelet‐activating factor: a mediator for clinicians ...1995-7-1 · F r o m tlrr Nora E d t s Harrison Cardiovasritlar Research and Training Institutt. thP Errks Program in Human MolPritlar Biologg and GPnPtirs. irnd tlrr rkpartrnrrirs OJ Irrtrrrral MPdicinr arid Biorhprnistrg. Univtrsit!/ OJ Utah. Salt LakP City. Utah, U S A Introduction Platelet-activating factor (PAF) is the common name given to l-O-alkyl-2-acetyl-sn-glycero-3 …

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Frontiers | Phytochemicals as Potential Epidrugs in Type 2 ...

Type 2 diabetes Mellitus (T2DM) prevalence has significantly increased worldwide in recent years due to population age, obesity, and modern sedentary lifestyles. The projections estimate that 439 million people will be diabetic in 2030. T2DM is characterized by an impaired β-pancreatic cell function and insulin secretion, hyperglycemia and insulin resistance, and recently the …Impact of Dysfunctional Protein Catabolism on …2020-12-31 · Title:Impact of Dysfunctional Protein Catabolism on Macrophage Cholesterol Handling VOLUME: 26 ISSUE: 9 Author(s):Takuro Miyazaki* and Akira Miyazaki Affiliation:Department of Biochemistry, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Department of Biochemistry, Showa University School of …

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Lentiviral vector-mediated siRNA knockdown of SR-PSOX ...

2008-7-1 · To investigate the expression of scavenger receptor that binds phosphatidylserine and oxidized lipoprotein (SR-PSOX)/CXC chemokine ligand 16 (CXCL16) in the human monocyte-derived cell line THP-1 .. tophagy is associated with cell fate in the process of ...2016-7-30 · Autophagy participates in plaque formation and progression; however, its association with foam cells'' fate is unknown. To investigate autophagy features and its effect on the fate of different-stage macrophage foam cells (FCs). Different-stage FCs were obtained through incubation of THP-1 macrophages (THP-M) with oxidized low-density lipoprotein LDL (oxLDL, …

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Autophagy is associated with cell fate in the process of ...

2016-7-30 · Autophagy participates in plaque formation and progression; however, its association with foam cells'' fate is unknown. To investigate autophagy features and its effect on the fate of different-stage macrophage foam cells (FCs). Different-stage FCs were obtained through incubation of THP-1 macrophages (THP-M) with oxidized low-density lipoprotein LDL (oxLDL, …Lentiviral vector-mediated siRNA knockdown of SR-PSOX ...2008-7-1 · To investigate the expression of scavenger receptor that binds phosphatidylserine and oxidized lipoprotein (SR-PSOX)/CXC chemokine ligand 16 (CXCL16) in the human monocyte-derived cell line THP-1 ...

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Platelet‐activating factor: a mediator for clinicians ...

1995-7-1 · F r o m tlrr Nora E d t s Harrison Cardiovasritlar Research and Training Institutt. thP Errks Program in Human MolPritlar Biologg and GPnPtirs. irnd tlrr rkpartrnrrirs OJ Irrtrrrral MPdicinr arid Biorhprnistrg. Univtrsit!/ OJ Utah. Salt LakP City. Utah, U S A Introduction Platelet-activating factor (PAF) is the common name given to l-O-alkyl-2-acetyl-sn-glycero-3 …Macrophage Lipid Uptake and Foam Cell FormationIn this chapter, various aspects of Mφ lipid metabolism and foam cell formation are explored. These include the sources of cholesterol for foam cell formation, receptor-dependent and receptor-independent uptake pathways by which foam cells may accumulate cholesterol, cholesterol trafficking within M φ, cholesterol efflux from M φ, and foam ...

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Macrophage impairment produced by Fc receptor gamma ...

2012-8-3 · Kenji Ito, Hitoshi Nakashima, Maho Watanabe, Atsunori Ishimura, Yoshito Miyahara, Yasuhiro Abe, Tetsuhiko Yasuno, Masakazu Ifuku, Yoshie Sasatomi, Takao Saito, Macrophage impairment produced by Fc receptor gamma deficiency plays a principal role in the development of lipoprotein glomerulopathy in concert with apoE abnormalities, Nephrology Dialysis …Platelet‐activating factor: a mediator for clinicians ...1995-7-1 · F r o m tlrr Nora E d t s Harrison Cardiovasritlar Research and Training Institutt. thP Errks Program in Human MolPritlar Biologg and GPnPtirs. irnd tlrr rkpartrnrrirs OJ Irrtrrrral MPdicinr arid Biorhprnistrg. Univtrsit!/ OJ Utah. Salt LakP City. Utah, U S A Introduction Platelet-activating factor (PAF) is the common name given to l-O-alkyl-2-acetyl-sn-glycero-3 …

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A novel small molecule, HK-156, inhibits ...

2012-6-11 · To characterize a small molecule compound HK-156 as a novel inhibitor of the nuclear factor κB (NF-κB) signaling pathway.THP-1 monocytes and HEK293/hTLR4A-MD2-CD14 cells were tested. HK-156 and compound 809, an HK-156 analogue, were synthesized. ...Toll-like receptor 7 promotes the apoptosis of THP-1 ...2014-7-3 · Macrophage apoptosis is a prominent characteristic of advanced atherosclerotic plaques and leads to plaque destabilization. Certain studies have confirmed that influenza virus A (IVA) infection is related to acute myocardial infarction (AMI). However, it remains unknown as to whether this phenomenon is associated with Toll-like receptor (TLR)7, since single-stranded …

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Toll-like receptor 7 promotes the apoptosis of THP-1 ...

2014-7-3 · Macrophage apoptosis is a prominent characteristic of advanced atherosclerotic plaques and leads to plaque destabilization. Certain studies have confirmed that influenza virus A (IVA) infection is related to acute myocardial infarction (AMI). However, it remains unknown as to whether this phenomenon is associated with Toll-like receptor (TLR)7, since single-stranded …Electronegative LDL Promotes Inflammation and …2020-3-1 · Reverse transcription was performed with 0.5 µg of RNA using EasyScript First-Stand cDNA Synthesis SuperMix (Transgen Biotech, Beijing, China). Quantitative RNA analysis was conducted using RT-PCR in a CFX96 system (BioRad, Hercules, CA, USA).

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A novel small molecule, HK-156, inhibits ...

2012-6-11 · To characterize a small molecule compound HK-156 as a novel inhibitor of the nuclear factor κB (NF-κB) signaling pathway. THP-1 monocytes … | - Sun Yat-sen University66 Ling WH, Lougheed M, Suzuki H, Buchan A, Kodama T, Steinbrecher Urs. Oxidized or acetylated low density lipoprotein are rapidly cleared by the liver in mice with disruption of the scavenger receptor class A typeI/II gene. J Clin Invest. 1997; 100:244-252. (IF

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Modified lipoproteins as biomarkers of atherosclerosis

2018-3-1 · 71. UP Steinbrecher, S Parthasarathy, DS Leake, JL Witztum, D Steinberg: Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids. Proc Natl Acad Sci U S A 81, 3883-3887 (1984) DOI: 10.1073/pnas.81.12.3883. 72.19 Aug 1949 - Advertising - TroveView all articles on this page. Previous article Next article ...

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Molecular Cloning of a Novel Scavenger Receptor for ...

2000-12-29 · From a cDNA library of phorbol 12-myristate 13-acetate-stimulated THP-1 cells, we isolated a cDNA encoding a novel protein designated SR-PSOX (scavenger receptor that bindsphosphatidylserine and oxidized lipoprotein), which acts as a receptor for OxLDL. SR-PSOX was a type I membrane protein consisting of 254 amino acids, expression of which was ...A novel small molecule, HK-156, inhibits ...2012-6-11 · THP-1 monocytes and HEK293/hTLR4A-MD2-CD14 cells were tested. HK-156 and compound 809, an HK-156 analogue, were synthesized. A luciferase assay was used to evaluate the transcriptional activity of NF-κB. The levels of cytokines were measured with cytokine arrays, ELISA and quantitative PCR.

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Role of Adiponectin‐Notch pathway in cognitive …

2021-5-30 · Haijing Yan, Department of Pharmacology, College of Basic Medicine, Binzhou Medical University, 264003 Yantai, China. Email: [email protected] . Jinbo Chen, Department of Neurology, Binzhou Medical University Hospital, 256603 Shandong, China. Email: [email protected] . Search for more papers by this authorHuman Monocyte–Derived Macrophages Express an ≈120 …1997-11-1 · This compares with 4000 to 8000 CD68 molecules per cell, expressed at the surface of phorbol myristate acetate–treated THP-1 cells. 20 Consistently the total number of Ox-LDL binding sites at the surface of human …

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Advanced Glycation End Products Induce Vascular Smooth ...

2020-8-7 · Steinbrecher U. P., Lougheed M., Kwan W. C., Dirks M. Recognition of oxidized low density lipoprotein by the scavenger receptor of macrophages results from derivatization of apolipoprotein B by products of fatty acid peroxidation. The Journal of Biological Chemistry. 1989; 264 (26):15216–15223. [Google Scholar]OxLDL stimulates lipoprotein-associated phospholipase A2 ...2009-11-12 · Using human monocytic THP-1 cells as a model system, we found that oxLDL up-regulated the expression of lp-PLA 2 while another substrate of the enzyme, platelet activating factor, had no such effect. The up-regulatory effect of oxLDL could be conferred by its oxidized phospholipids (oxPCs, the exact substrates of lp-PLA 2), but not their hydrolyzed products, …

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Macrophage scavenger receptor class A: A multifunctional ...

Macrophage scavenger receptor class A is thought to be one of the main receptors involved in foam cell formation, mediating the influx of lipids into the macrophages, and has been shown to be important in the inflammatory response in host defense, cellular activation, adhesion, and cell-cell interaction. In atherogenesis, elevated plasma levels of low density lipoprotein (LDL) lead …19 Aug 1949 - Advertising - TroveView all articles on this page. Previous article Next article ...

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A novel small molecule, HK-156, inhibits ...

2012-6-11 · To characterize a small molecule compound HK-156 as a novel inhibitor of the nuclear factor κB (NF-κB) signaling pathway.THP-1 monocytes and HEK293/hTLR4A-MD2-CD14 cells were tested. HK-156 and compound 809, an HK-156 analogue, were synthesized. ...Specific Kv1.3 blockade modulates key cholesterol ...2013-1-1 · After differentiation, THP-1 macrophages or HMDMs were exposed to 100 μg/ml ox-LDL in the presence of the hKv1.3-E314 antibody at varying concentrations of 37.5, 75, or 300 nM for 2 h. THP-1 macrophages or HMDMs were exposed to 100 μg/ml ox-LDL for 24 h to accelerate foam cell formation with less toxicity or apoptosis (33, 34). Meanwhile, to ...

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Advanced Glycation End Products Induce Vascular Smooth ...

2020-8-7 · Steinbrecher U. P., Lougheed M., Kwan W. C., Dirks M. Recognition of oxidized low density lipoprotein by the scavenger receptor of macrophages results from derivatization of apolipoprotein B by products of fatty acid peroxidation. The Journal of Biological Chemistry. 1989; 264 (26):15216–15223. [Google Scholar]hand 200 tph stone crusher - auto-gaz-slask.plStabile Leistung 150 tph Stone Rock Pebble Crusher THP 300 200 Hydraulik kegel brecher Preis. 1.256,00 $8.456,00 $ / Satz. 1 Satz (Mindestbestellung) Zhengzhou General Mining Machinery Co., Ltd. CN 13 YRS.

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Beste Qualität 200 TPH steinbrecher

Über Produkt und Lieferanten: Kauf 200 TPH steinbrecher. von zertifizierten Anbietern nur auf Alibaba . Metalle gehören zum Alltag, von Utensilien über Schmuck bis hin zu Baumaterial.Wenn der Rohstoff nicht ordnungsgemäß verarbeitet wird, besteht eine hohe Wahrscheinlichkeit, dass die Endprodukte nicht fest oder haltbar sind.Toll-like receptor 7 promotes the apoptosis of THP-1 ...2012-6-11 · To characterize a small molecule compound HK-156 as a novel inhibitor of the nuclear factor κB (NF-κB) signaling pathway.THP-1 monocytes and HEK293/hTLR4A-MD2-CD14 cells were tested. HK-156 and compound 809, an HK-156 analogue, were synthesized. ...

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hand 200 tph stone crusher

Stabile Leistung 150 tph Stone Rock Pebble Crusher THP 300 200 Hydraulik kegel brecher Preis. 1.256,00 $8.456,00 $ / Satz. 1 Satz (Mindestbestellung) Zhengzhou General Mining Machinery Co., Ltd. CN 13 YRS.Function of different proportions of apolipoprotein A-I ...Abstract. To explore the anti-atherosclerotic effects of recombinant high-density lipoproteins (rHDL) of apolipoprotein AI wild-type (apoA-Iwt), apolipoprotein AI Milano (apoA-IM), apolipoprotein AI (N74C) (apoA-I (N74C) )and apolipoprotein AV (apoA-V). We constructed rHDL liposomes (rHDLs), which included apoA-Iwt, apoA-IM, and apoA-I (N74C), followed by the …

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Human Monocyte–Derived Macrophages Express an ≈120 …

1997-11-1 · This compares with 4000 to 8000 CD68 molecules per cell, expressed at the surface of phorbol myristate acetate–treated THP-1 cells. 20 Consistently the total number of Ox-LDL binding sites at the surface of human …Molecular Cloning of a Novel Scavenger Receptor for ...2000-12-29 · From a cDNA library of phorbol 12-myristate 13-acetate-stimulated THP-1 cells, we isolated a cDNA encoding a novel protein designated SR-PSOX (scavenger receptor that bindsphosphatidylserine and oxidized lipoprotein), which acts as a receptor for OxLDL. SR-PSOX was a type I membrane protein consisting of 254 amino acids, expression of which was ...

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